Dysregulation of Whole-body Metabolism in Ovarian Cancer: A Longitudinal Study
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
Minimal information is available regarding changes in whole-body metabolism in ovarian cancer patients, and no study has assessed whole-body lipid metabolism in this patient population. In this pilot study we will assess fasting and postprandial lipid metabolism of ovarian cancer patients before, during, and after treatment via indirect calorimetry.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:
• Women
• Age \>18
• Presumed ovarian cancer diagnosis (i.e. those being clinically evaluated for suspicion of ovary cancer)
• Planned treatment course for ovarian cancer involving cytoreductive surgery followed by chemotherapy
• Availability to commit to attending all study visits
• Internet access and consistent access to phone/email/text communication
Locations
United States
Tennessee
University of Tennessee Graduate School of Medicine
RECRUITING
Knoxville
Contact Information
Primary
Jill M Maples, PhD
jmaples1@utmck.edu
8653059367
Time Frame
Start Date: 2023-03-22
Estimated Completion Date: 2028-03-31
Participants
Target number of participants: 10
Treatments
Patients with presumed ovarian cancer
Patients with presumed ovarian cancer will complete three, 4-hour study visits at the following time points:~* The 1st visit will occur before treatment.~* The 2nd visit will occur after about half of the planned treatment as been completed.~* The 3rd visit will occur 4-8 weeks after the completion of treatment.
Related Therapeutic Areas
Sponsors
Leads: University of Tennessee Graduate School of Medicine