A Multi-center, Randomized, Open-label, Controlled, Phase III Clinical Study Evaluating HS-20089 vs. Investigator's Choice of Chemotherapy in the Treatment of Platinum-resistant Recurrent Epithelial Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

This study is a randomized, open-label, controlled, phase III study to evaluate the efficacy and safety of HS-20089 versus investigator's choice of chemotherapy in patients with platinum-resistant recurrent epithelial ovarian cancer.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:

• Voluntary participation and written informed consent.

• 18 years and older, female.

• Pathologically diagnosed epithelial ovarian cancer, primary peritoneal cancer, or fallopian tube cancer.

• Patients must have platinum-resistant disease

• Be able to provide fresh or archived tumor tissue.

• At least one measurable lesion according to RECIST v1.1.

• Eastern Cooperative Oncology Group (ECOG) score: 0-1.

• With a life expectancy \> 12 weeks.

• Adequate bone marrow reserve and organ function.

⁃ Contraception is required during the trial.

Locations
Other Locations
China
Cancer Hospital, Chinese Academy of Medical Sciences
RECRUITING
Beijing
Contact Information
Primary
Lingying Wu, MD
wulingying@csco.org.cn
(+86)13910865483
Time Frame
Start Date: 2025-03-13
Estimated Completion Date: 2029-03-07
Participants
Target number of participants: 468
Treatments
Experimental: Treatment group 1: HS-20089
Active_comparator: Treatment group 2: Investigator's choice of chemotherapy
Related Therapeutic Areas
Sponsors
Leads: Hansoh BioMedical R&D Company

This content was sourced from clinicaltrials.gov