Rehabilitation of Airway Protection in Parkinson's Disease: Comparing In-person and Telehealth Service Delivery Models

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

Airway protective disorders are a prevalent and progressive consequence of Parkinson's Disease (PD), and often result in aspiration pneumonia which is the leading cause of death in PD. Despite this, a large number of patients with PD do not access specialized services to address these critical deficits. The investigators will examine the comparative effectiveness of a novel treatment paradigm delivered in-person versus via telehealth in persons with PD, as well as the role of patient burden and treatment adherence on outcomes; thus, the proposed research is relevant to public health and in line with NIH's mission to identify novel, efficacious, and accessible rehabilitation strategies for short- and long-term improvement of dysfunctional airway protection in PD.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Maximum Age: 90
Healthy Volunteers: f
View:

• Diagnosed with PD (Hoehn and Yahr Stages II-IV)126,127 confirmed by a Movement Disorders fellowship trained neurologist having reviewed the video recorded Movement Disorders Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) assessment for each participant and using strict UK brain bank criteria

• airway protective deficits as defined as a minimum of penetration of thin liquids (penetration-aspiration score\>3) as determined by instrumental swallowing assessment and/or dystussia as determined by voluntary cough assessment (PEFR ≤4.1 L/s)

• not actively receiving exercise-based swallowing therapy

• between the ages of 50 and 90.

Locations
United States
Indiana
Purdue University
RECRUITING
West Lafayette
New York
Teachers College, Columbia University
ACTIVE_NOT_RECRUITING
New York
Contact Information
Primary
Michelle Troche, PhD
uadlab@tc.columbia.edu
212-678-3072
Time Frame
Start Date: 2022-08-11
Estimated Completion Date: 2027-09-01
Participants
Target number of participants: 120
Treatments
Active_comparator: In-person
Experimental: Telehealth
Sponsors
Collaborators: Purdue University, National Institute of Neurological Disorders and Stroke (NINDS)
Leads: Teachers College, Columbia University

This content was sourced from clinicaltrials.gov