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Nutritional Intervention for Constipation Symptoms in Patients With Parkinson's Disease: A Randomized Clinical Trial

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to evaluate whether a dietitian-guided nutritional intervention can improve constipation symptoms in people with Parkinson's disease (PD). The main questions it aims to answer are: * Can a dietitian-guided nutritional intervention increase the number of weekly bowel movements in individuals with PD and functional constipation? * Can this intervention positively influence gut microbiota composition, dietary intake, and nutritional status? Researchers will compare the intervention group to a control group that will receive general dietary guidance only after the study period, to see if the intervention leads to improvements in bowel function and related health outcomes. Participants will: * Follow a diet plan developed by a dietitian, based on dietary reference intakes and tailored to the needs of individuals with PD and constipation * Participate in follow-up sessions with the dietitian for 3 months * Complete assessments at baseline, midpoint, and end of the intervention to evaluate bowel function, constipation symptoms, gut microbiota, nutritional status, and diet quality

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adults with a previous diagnosis of Parkinson's disease

• On a stable dose of levodopa for at least 3 months

• Diagnosis of Functional Constipation by the Rome IV protocol

Locations
Other Locations
Brazil
Hospital de Clínicas de Porto Alegre (HCPA)
RECRUITING
Porto Alegre
Contact Information
Primary
Maira Rozenfeld Olchik, PhD
molchik@hcpa.edu.br
+55 (51) 33083020
Time Frame
Start Date: 2026-04-02
Estimated Completion Date: 2029-08
Participants
Target number of participants: 54
Treatments
Experimental: Nutritional Intervention Group
Participants will receive a tailored diet plan made by a registered dietitian, with follow-ups for 3 months. The plan is based on Dietary Reference Intakes and adapted to Parkinson's disease and constipation management guidelines.
No_intervention: Control Group
Participants will not receive individualized nutritional support during the study period. They will receive the dietary guidance only after the end of the study (3 months).
Sponsors
Leads: Hospital de Clinicas de Porto Alegre

This content was sourced from clinicaltrials.gov