Zesty Exercise System for Therapeutic Engagement
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study will evaluate exercise delivered through the Zesty Exercise System for Therapeutic Engagement (ZEST-E) for people with Parkinson's disease when sessions are monitored either in person or remotely. Participants will complete robot-guided exercise three times per week for three weeks. The study will assess feasibility, retention, safety, acceptability, and tolerability of remotely monitored ZEST-E and will measure changes in functional performance using the Standing Forward Reach test and the 30-Second Chair Stand test. These outcomes reflect range of motion and lower-body strength targeted by the exercise program.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Healthy Volunteers: f
View:
• Older adults with mild to moderate PD.
Locations
United States
Georgia
Emory University, 57 Executive Park S NE, Ste 200
RECRUITING
Atlanta
Contact Information
Primary
Madeleine Hackney, PhD
mehackn@emory.edu
314-412-4852
Backup
Hannah Kim
hannah.kim3@emory.edu
Time Frame
Start Date: 2026-03-16
Estimated Completion Date: 2028-02
Participants
Target number of participants: 46
Treatments
Experimental: In-Person Monitored ZEST-E Exercise
Participants complete ZEST-E exercise sessions with a researcher or physical therapist present in the same room to provide safety oversight. All participants begin with seated exercises in week 1 and may progress to standing exercises in weeks 2 and 3 after completing a safety tutorial and demonstrating understanding of standing-exercise precautions. The researcher monitors the robot, provides instructions, and may stop the robot at any time using the run-stop button if needed.
Experimental: Remotely Monitored ZEST-E Exercise
Participants complete ZEST-E exercise sessions while the researcher or physical therapist monitors the session remotely via camera from outside the room. A trained caregiver is present in the room to provide safety oversight and to activate the robot's run-stop button if needed. Participants follow the same progression from seated to standing exercises as in the in-person arm, contingent on completion of the safety tutorial and demonstration of safe technique.
Related Therapeutic Areas
Sponsors
Collaborators: Georgia Clinical & Translational Science Alliance
Leads: Emory University