Parkinson's Disease Clinical Trials

Find Parkinson's Disease Clinical Trials Near You

Sensing in Sleep and Deep Brain Stimulation

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Participants in this study have Parkinson's Disease and already have a device, called the Percept RC Deep Brain Stimulation device implanted. People with Parkinson's disease often have issues related to sleep such as bad quality of sleep, waking up often and sleep apnea (breathing stops and starts during sleep). For this study, participants will be sleeping overnight in the study sleep lab for two nights. One night, Deep Brain Stimulation (DBS) device turned on and one night with the DBS off, either in this order or the reverse.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 80
Healthy Volunteers: f
View:

• Ability of subject to understand and the willingness to sign a written informed consent document.

• Males and females; Age 40-80

• Subjects with the diagnosis of idiopathic PD consistent with the United Kingdom Parkinson Disease society brain bank criteria, or documented diagnosis of Parkinson Disease who have a Deep Brain Implant, Percept RC device to subthalamic nucleus (STN) or Globus pallidus internus (GPi).

• Willingness to adhere to the PSG regimen and turn DBS off for one night.

• A score of ≥23 on the Montreal Cognitive Assessment (MoCA)

• Be willing to stop any sleep hypnotics such as benzodiazepines and Ambien, with a 3 day washout period.

Locations
United States
Texas
The University of Texas Health Science Center at San Antonio - Brain Health Center
RECRUITING
San Antonio
Contact Information
Primary
Eleni O Vaou, MD
vaou@uthscsa.edu
210 450 8048
Backup
Omalys Biggs Rodriguez
biggsrodrigu@uthscsa.edu
210-450-7547
Time Frame
Start Date: 2026-02-27
Estimated Completion Date: 2028-02-01
Participants
Target number of participants: 20
Treatments
Experimental: STN-DBS Group
Participants diagnosed with Parkinson's Disease who have subthalamic nucleus (STN) deep brain stimulation as a primary target for their condition
Experimental: GPi-DBS Group
Participants diagnosed with Parkinson's Disease who have Globus Pallidus internus (GPi) deep brain stimulation as a primary target for their condition.
Sponsors
Leads: The University of Texas Health Science Center at San Antonio

This content was sourced from clinicaltrials.gov