Validation of ICG-99mTc-nanoscan as Hybrid Tracer for Sentinel Node Biopsy
99mTc-nanocolloid, the world wide used hybrid tracer for dynamic sentinel node biopsy, has recently been replaced with 99mTc-nanoscan. The hybrid form (ICG-99mTc-nanoscan) has not yet been validated, to show the similarity between the lymphatic drainage pattern between ICG-99mTc-nanoscan and 99mTc-nanoscan.
• Patient who will undergo a sentinel node procedure in routine care.
• Patients \> 18 years;
• Patients presenting with:
• a primary cutaneous melanoma of head/neck or upper part of the trunk or extremities;
• OR patients presenting with a primary oral cavity malignancy T1-2N0
• OR patients with primary penile cancer
• Patients with clinical N0 stage;
• Patients scheduled for a sentinel node biopsy prior to (re-)excision of the primary lesion;
• Patients in which ICG-99mTc-nanoscan would be used in routine care or a research setting