PEPCK 1 Deficiency Latest Advances

Find the Latest Research About PEPCK 1 Deficiency

Last Updated: 04/28/2026

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Found 62 publications

Pck1 Deficiency Drives Mitochondrial Dysfunction and Cellular Senescence in Adipocytes.

Pck1 Deficiency Drives Mitochondrial Dysfunction and Cellular Senescence in Adipocytes.

Journal: Aging cell
Published: September 04, 2025

Round and round we go: phosphoenolpyruvate carboxykinase 1 (PCK1) in cataplerosis, mitochondrial, and kidney health.

Round and round we go: phosphoenolpyruvate carboxykinase 1 (PCK1) in cataplerosis, mitochondrial, and kidney health.

Journal: Kidney international
Published: July 13, 2025

Transcriptional and epigenetic responses to acute hypoxia exposure in rainbow trout (Oncorhynchus mykiss).

Transcriptional and epigenetic responses to acute hypoxia exposure in rainbow trout (Oncorhynchus mykiss).

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Published: May 15, 2025

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non-Finnish Patients.

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non-Finnish Patients.

Journal: American journal of medical genetics. Part A
Published: May 15, 2025

Notoginsenoside R1 Improved Hypoxic Pulmonary Hypertension by Inhibiting Glycolysis-Mediated Pulmonary Arterial Vascular Remodeling.

Notoginsenoside R1 Improved Hypoxic Pulmonary Hypertension by Inhibiting Glycolysis-Mediated Pulmonary Arterial Vascular Remodeling.

Journal: Canadian respiratory journal
Published: April 09, 2025

Decreased expression of insulin-degrading enzyme increases gluconeogenesis and glucose production in cultured hepatocytes administered with glucagon.

Decreased expression of insulin-degrading enzyme increases gluconeogenesis and glucose production in cultured hepatocytes administered with glucagon.

Journal: Scientific reports
Published: March 17, 2025

A Novel PCK1 Gene Variant Associated With Cytosolic Phosphoenolpyruvate Carboxykinase Deficiency: Two Siblings With Different Clinical Presentations.

A Novel PCK1 Gene Variant Associated With Cytosolic Phosphoenolpyruvate Carboxykinase Deficiency: Two Siblings With Different Clinical Presentations.

Journal: JIMD reports
Published: February 27, 2025

PCK1 deficiency promotes MASH-HCC progression by 12-HETE-induced CD8+ T cell dysfunction.

PCK1 deficiency promotes MASH-HCC progression by 12-HETE-induced CD8+ T cell dysfunction.

Journal: Gut
Published: December 10, 2024

The neglected PCK1/glucagon (inter)action in nutrient homeostasis beyond gluconeogenesis: Disease pathogenesis and treatment.

The neglected PCK1/glucagon (inter)action in nutrient homeostasis beyond gluconeogenesis: Disease pathogenesis and treatment.

Journal: Molecular metabolism
Published: November 30, 2024

Cytosolic PEPCK deficiency caused by a novel homozygous frame-shift variant presenting as resolved hypoglycemia and acute liver failure at birth.

Cytosolic PEPCK deficiency caused by a novel homozygous frame-shift variant presenting as resolved hypoglycemia and acute liver failure at birth.

Journal: Molecular genetics and metabolism reports
Published: October 02, 2024

Phosphoenolpyruvate carboxykinase 1-mediated cataplerosis is required to maintain mitochondrial fitness and to avoid kidney disease progression.

Phosphoenolpyruvate carboxykinase 1-mediated cataplerosis is required to maintain mitochondrial fitness and to avoid kidney disease progression.

Journal: Kidney international
Published: September 09, 2024

Hepatocyte-specific RIG-I loss attenuates metabolic dysfunction-associated steatotic liver disease in mice via changes in mitochondrial respiration and metabolite profiles.

Hepatocyte-specific RIG-I loss attenuates metabolic dysfunction-associated steatotic liver disease in mice via changes in mitochondrial respiration and metabolite profiles.

Journal: Toxicological research
Published: June 21, 2024
Showing 1-12 of 62

Last Updated: 04/28/2026