Evaluation of Anti-plaque and Anti-inflammatory Effects of Green Tea and Salvadora Persica L. in Patients With Gingivitis

Status: Recruiting
Location: See location...
Intervention Type: Other, Drug
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

Gingivitis is an inflammatory condition of the gingival tissue, most commonly caused by bacterial infection.The plaque control is considered the most important preventive factor concerning caries, gingivitis, and periodontitis Mechanical means of plaque control, e.g. tooth brushing, flossing and use of other mechanical devices are the most commonly used methods. However, ideal plaque control solely by mechanical means requires a significant effort and is difficult to achieve.This has led to the introduction of chemical methods of plaque control using antimicrobial agentsMore specifically, chemotherapeutic agents with antimicrobial properties, such as 0.12% chlorhexidine (CHX).chx has side effects encourage the need to develop alternative mouthwashes with similar efficacy but without these issues.hence the mouthwash enriched with a combination of aqueous extracts of Salvadora persica L. and green tea used as a substitution to CHX with minimal side effects .The objective of this study was to investigate the efficacy of the combination of Gt aqueous extract and Sp aqueous extract in reducing plaque buildup and gingivitis for 4 weeks duration.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 15
Maximum Age: 55
Healthy Volunteers: t
View:

• Subjects aged more than 15 years-old who will volunteer to participate.

• Participants who were apparently systemically healthy.

• Not taking antibiotic and anti-inflammatory drugs in the last three months

• Patients having generalized gingivitis with intact periodontium in which they have more than 30% bleeding sites with no PPD \>3 mm with no clinical attachment loss according to criteria proposed by

Locations
Other Locations
Iraq
Aliaa
RECRUITING
Baghdad
Time Frame
Start Date: 2024-01-01
Estimated Completion Date: 2024-07
Participants
Target number of participants: 45
Treatments
Active_comparator: co.mouthwash
15ml twice a day, rinse for 30sec refrain from eating or drinking for 30min
Placebo_comparator: Kin mouthwash
15ml twice a day, rinse for 30sec refrain from eating or drinking for 30min
Placebo_comparator: Distilled water
15ml twice a day, rinse for 30sec refrain from eating or drinking for 30min
Related Therapeutic Areas
Sponsors
Leads: University of Baghdad

This content was sourced from clinicaltrials.gov