Effectiveness of Asiaticoside as Intracanal Medication on Infectious/Inflammatory Contents in Teeth With Apical Periodontitis
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2/Phase 3
SUMMARY
The objective of this study is to investigate \"clinically\" the effectiveness of Asiaticoside based intracanal medication compared to the commonly used intracanal medicaments (calcium hydroxide Ca(OH)2 and Ledermix) on the levels of bacteria and inflammatory cytokines in root canals and periradicular tissues of teeth with apical periodontitis.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Maximum Age: 60
Healthy Volunteers: t
View:
• • Single-rooted with pulp necrosis and apical periodontitis.
Locations
Other Locations
Egypt
Mansoura university
RECRUITING
Al Mansurah
Contact Information
Primary
salem alqahtani, master
Salemamq@gmail.com
00201553553096
Backup
Ghada Abdelrazik
Salemamq@gmail.com
00201003455012
Time Frame
Start Date: 2023-11-20
Estimated Completion Date: 2025-03-03
Participants
Target number of participants: 36
Treatments
Active_comparator: Calcium Hydroxide
Intracanal medication
Active_comparator: Leddermix
Intracanal medication
Active_comparator: Asiaticoside
Intracanal medication
Related Therapeutic Areas
Sponsors
Leads: Mansoura University