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Effect of Calcium-Based Bioceramic Sealer and Resin-Based Sealer on Postoperative Pain in Adults With Asymptomatic Apical Periodontitis

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study aims to compare the effect of calcium-based bioceramic sealer and resin-based sealer on postoperative pain in adult patients with asymptomatic apical periodontitis undergoing root canal treatment. Asymptomatic apical periodontitis is a condition where the tissue around the tip of the tooth root is inflamed or shows a lesion on X-ray, but the patient does not experience pain. A total of 60 patients will be randomly assigned to receive root canal treatment with either the bioceramic sealer (Group A) or the resin-based sealer (Group B). Pain after treatment will be measured using a 0-10 Numeric Pain Rating Scale at 4, 24, and 48 hours post-treatment. The highest pain score reported will determine whether the treatment is considered a success (no or mild/moderate pain) or failure (severe pain). The results of this study will provide evidence on which sealer is associated with less postoperative pain, helping clinicians make informed decisions about root canal filling materials.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 55
Healthy Volunteers: f
View:

• Both genders.

• Teeth diagnosed with asymptomatic apical periodontitis.

• Teeth are asymptomatic (no pain on percussion or palpation).

• Non-vital pulp (no response on Electric Pulp Testing).

• Teeth with fully formed apices.

• Teeth with Periapical Index (PAI) scores 2-4 on radiographs.

Locations
Other Locations
Pakistan
Fatima Memorial Hospital
RECRUITING
Lahore
Contact Information
Primary
Shehryar Khan, Bachelor Of Dental SURGERY
shehryar_jadun@yahoo.com
+92 336 9892535
Time Frame
Start Date: 2025-12-01
Estimated Completion Date: 2026-02-28
Participants
Target number of participants: 60
Treatments
Experimental: Bioceramic Sealer Group
Patients in this group will receive root canal obturation using bioceramic (calcium silicate-based) sealer with gutta-percha. Postoperative pain will be assessed at 4, 24, and 48 hours using the Numeric Pain Rating Scale (NPRS).
Experimental: Resin-Based Sealer Group
Patients in this group will receive root canal obturation using resin-based sealer with gutta-percha. Postoperative pain will be assessed at 4, 24, and 48 hours using the Numeric Pain Rating Scale (NPRS).
Related Therapeutic Areas
Sponsors
Leads: Fatima Memorial Hospital

This content was sourced from clinicaltrials.gov