A Pilot Study to Test the Efficacy of a Commercial Toothpaste (Cosmetic Product)
This clinical multi-center, controlled, study will be carried out in volunteers with every 3- to 6-months professional tooth cleaning during their non-treatment period between 2 re-calls of a supportive periodontitis therapy regime. The efficacy of domestic oral hygiene by using a commercial dentifrice will be determined. Besides regularly used ingredients such as NaF and cleaning bodies the dentifrice contains a novel compound, which may be beneficial for the protection of an eubiotic oral microbiome. During the 3-month study period, participants will brush with their allocated study product twice daily.
• Demonstrates understanding of the study procedures, restrictions and willingness to participate as evidenced by voluntary written informed consent and has received a signed and dated copy of the informed consent form.
• Good general health with no clinically significant and relevant abnormalities of medical history.
• Absence of any condition that would impact on the subject's safety or wellbeing or affect the individual's ability to understand and follow study procedures and requirements.
⁃ At Screening (Visit 1):
• Participant with at least 16 natural, permanent teeth.
• A participant who gets regularly professional tooth cleaning in a frequence of once to twice yearly.
• Participant whose biofilm contains at least Porphyromonas gingivalis.