Understanding and Preventing Cortical Mechanisms of Chemotherapy-induced Peripheral Neuropathy
Cohort 1: To track the onset and progression of a condition called chemotherapy-induced peripheral neuropathy (CIPN). Cohort 2: To track the onset and progression of a condition called chemotherapy-induced peripheral neuropathy (CIPN) and to test a certain type of experimental neuromodulation (stimulation of the brain) with a device called a closed-loop brain-computer interface (clBCI) to see if can help to prevent pain due to CIPN.
⁃ Objective 1 Inclusion criteria
• Participants must have the ability to understand and read English, sign a written informed consent, and be willing to follow protocol requirements.
• ECOG Performance Status of 0-2;
• Willing to come to MD Anderson for the imaging sessions.
• Are 18 years of age or above.
• Have a diagnosis of breast cancer.
• will receive chemotherapy including doxorubicin, cyclophosphamide, docetaxel, or paclitaxel;
⁃ Objective 2 Inclusion criteria:
⁃ 1\) Inclusion criteria: Identical to Objective 1 and are willing to participate in the therapy sessions at their homes.