The Role Of Great Toe Strength And Its Association With The Severity Of Symptoms Of Chemotherapy-Induced Peripheral Neuropathy (CIPN)

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Great Toe Strength (GTS) is a potential clinical biomarker that has been associated with functional mobility and health; Additionally, GTS has been identified in the literature as one of the early symptoms of chemotherapy-induced peripheral neuropathy (CIPN). The purpose of this research study is to evaluate GTS in individuals with CIPN and healthy adults using ToeScale and see how it relates to nerve issues from chemotherapy. Additionally, we aim to assess the usability of the novel GTS assessment device, ToeScale among the participants. As a part of this study visit, you will complete some questionnaires followed by GTS and balance and gait assessments.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: t
View:

• At least 18 years of old with the ability to independently raise and low (extend or flex) the great toe

• Able to consent and complete questionnaires in English independently and have normal to corrected vision (self-reported)

• Within 3 - 6 months of starting chemotherapy and a confirmed diagnosis of CIPN using the current clinical reference standard of Nerve conduction study.

Locations
United States
Florida
University of Florida
RECRUITING
Gainesville
Contact Information
Primary
Hongwu Wang, PhD
hongwu.wang@phhp.ufl.edu
+1 (352) 273-9934
Backup
Raghuveer Chandrashekhar, MS
rchandrashekhar@ufl.edu
Time Frame
Start Date: 2025-08-05
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 30
Treatments
CIPN
Individuals with chemotherapy-induced peripheral neuropathy with a confirmed diagnosis using the nerve conduction study
Healthy
Healthy adults with no known health conditions affecting their mobility, balance, or lower extremity muscle strength
Related Therapeutic Areas
Sponsors
Leads: University of Florida

This content was sourced from clinicaltrials.gov