The Role of Transient Receptor Potential Channels in Diabetic Peripheral Neuropathy
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
The study aims to characterize the vascular response upon topical application of cinnamaldehyde, allyl isothiocyanate and capsaicin on feet skin in healthy volunteers. The vascular response will be characterized in terms of response over time, dose-response, inter-foot and inter-period reproducibility.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: t
View:
• Subject is a white male or female ≥18 and ≤45 years of age
• Subject is a non-smoker for at least 6 months prior to the start of the study
• Subject has a body mass index (BMI) between 18-30 kg/m²
• Subject is judged to be in good general health on the basis of medical history, physical examination and vital signs
• Subject understands the procedures and agrees to participate in the study by giving written informed consent.
Locations
Other Locations
Belgium
Center for Clinical Pharmacology
RECRUITING
Leuven
Contact Information
Primary
Heleen Marynissen
heleen.marynissen@uzleuven.be
+3216347014
Time Frame
Start Date: 2025-10-08
Estimated Completion Date: 2026-08-31
Participants
Target number of participants: 20
Related Therapeutic Areas
Sponsors
Leads: Universitaire Ziekenhuizen KU Leuven