Peritonitis Clinical Trials

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Impact of Synbiotic Supplementation in Peritoneal Dialysis Patients

Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn if synbiotics work to lower inflammation in adults with chronic kidney disease who are on peritoneal dialysis. Synbiotics are daily capsules that contain a mix of probiotics (good bacteria) and prebiotics (fiber that feeds good bacteria). The main questions it aims to answer are: Do synbiotics lower the level of inflammation markers in the blood? Do synbiotics improve the nutritional status of the participants? Do synbiotics lower the number of peritonitis (peritoneal infections) episodes? Researchers will compare synbiotics to a placebo to see if the treatment works. A placebo is a look-alike capsule that contains no active ingredients. Participants will: Take 1 capsule every day for 6 months Visit the clinic at the start, at 3 months, and at 6 months for blood tests and nutrition checkups

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients aged 18 years or older.

• Patients diagnosed with kidney disease who have been receiving peritoneal dialysis at home for at least 1 month.

Locations
Other Locations
Mexico
Hospital Universitario Dr. José E. González, Centro Regional de Enfermedades Renales (CRER)
RECRUITING
Monterrey
Contact Information
Primary
Elisa María Guadalupe Guerrero González, MD
eguerrerog@uanl.edu.mx
528182803788
Backup
Giovanna Yazmín Arteaga Müller, MD, PhD
giomuller@gmail.com
528112512168
Time Frame
Start Date: 2025-10-03
Estimated Completion Date: 2027-06
Participants
Target number of participants: 60
Treatments
Placebo_comparator: Placebo
Participants assigned to this arm will receive one identical, inactive oral capsule daily for a period of 6 months.
Experimental: Synbiotic
Participants assigned to this arm will receive one oral capsule daily for a period of 6 months. Each capsule contains a combination of probiotic strains and prebiotic fibers.
Related Therapeutic Areas
Sponsors
Leads: Hospital Universitario Dr. Jose E. Gonzalez

This content was sourced from clinicaltrials.gov