Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain.Home-Based Treatment

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

After amputation of an arm or leg, up to 90% of subjects experience a phantom limb, a phenomenon characterized by persistent feelings of the missing limb. Many subjects with a phantom limb experience intense pain in the missing extremity that is often poorly responsive to medications or other interventions. The study will explore the feasibility and efficacy of a home-based, active VR treatment for phantom limb pain (PLP).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 100
Healthy Volunteers: f
View:

• Age 18 -100

• Capacity to provide Informed Consent

• Unilateral above or below knee amputation more than 3 months prior to enrollment

• Absence of cognitive impairment, operationally defined as a Montreal Cognitive Assessment score of 18 or greater1.

• Pain averaged over the preceding 1 month in the phantom limb rated as greater than 4 on a scale of 0-10.

Locations
United States
Pennsylvania
Jefferson Moss Rehabilitation Research Institute
RECRUITING
Philadelphia
University of Pennsylvania
RECRUITING
Philadelphia
Washington
University of Washington
RECRUITING
Seattle
Contact Information
Primary
Laurel Buxbaum
Laurel.Buxbaum@jefferson.edu
215-663-6321
Time Frame
Start Date: 2025-06-16
Estimated Completion Date: 2026-05-31
Participants
Target number of participants: 44
Treatments
Experimental: Home-based treatment
Self-administered Active Virtual Reality treatment
Related Therapeutic Areas
Sponsors
Leads: Albert Einstein Healthcare Network
Collaborators: University of Pennsylvania

This content was sourced from clinicaltrials.gov

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