Phenylketonuria (PKU) Clinical Trials

Find Phenylketonuria (PKU) Clinical Trials Near You

Effect of Different Meal Types Given Before Exercise on Plasma Amino Acid Levels and Metabolic Control Parameters in Classical Phenylketonuria Patients Undergoing Aerobic and Resistance Exercises

Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement, Behavioral, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study will be the first in the literature to evaluate the relationship between aerobic and resistance exercises, plasma amino acid levels, metabolic control of patients, and the metabolic response to exercise with different types of meals in patients with Phenylketonuria (PKU). In patients with phenylketonuria, the aim is to determine which pre-exercise dietary recommendations are more physiologically appropriate and ideal for achieving good metabolic control. In the literature, there are very few studies examining the effects of exercise on plasma amino acid levels and metabolic parameters in PKU patients.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Be over 18 years old,

• Having a classic FKU diagnosis,

• Not being actively engaged in sports,

• Not having any other existing diseases,

• Not having an active infection,

• Have a BMI in the range of 20-28 kg/m2 within the last 3 months,

• Agreeing to consume test meals and provide blood samples for parameters that will evaluate plasma amino acid levels as part of the research

• Being willing to participate in this study

Locations
Other Locations
Turkey
Hacettepe University
RECRUITING
Ankara
Contact Information
Primary
DAMLA KALKAN, MSc, PhD(c)
damla.yildirim@hacettepe.edu.tr
+905543528779
Time Frame
Start Date: 2025-10-01
Estimated Completion Date: 2026-07-15
Participants
Target number of participants: 10
Treatments
Experimental: Aerobic Exercise + Water
Participants performed aerobic exercise after consuming only water.
Experimental: Aerobic Exercise + Carbohydrates
Participants performed aerobic exercise after consuming carbohydrates with water.
Experimental: Aerobic Exercise + Carbohydrates + Protein
Participants performed aerobic exercise after consuming carbohydrates and protein with water.
Experimental: Resistance Exercise + Water
Participants performed resistance exercise after consuming only water.
Experimental: Resistance Exercise + Carbohydrates
Participants performed resistance exercise after consuming carbohydrates with water.
Experimental: Resistance Exercise + Carbohydrates + Protein
Participants performed resistance exercise after consuming carbohydrates and protein with water.
Related Therapeutic Areas
Sponsors
Leads: Hacettepe University

This content was sourced from clinicaltrials.gov