Defining Protein Requirements in Adults With PKU: Impact of Genotype and Medical Food Intake
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The objective of this research is to determine the protein requirements based on genotype and medical food consumption in a sample of adults with Phenylketonuria (PKU) using the indicator amino acid oxidation (IAAO) method.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• will be males and females (50:50) 18 years and older who were diagnosed with PKU through newborn screening or diagnosis later in life, capable of providing consent, and have previously had mutation testing
Locations
United States
Georgia
Emory University Hospital
RECRUITING
Atlanta
Contact Information
Primary
Jessica Strosahl, PhD, RDN, LD
jessica.nash.strosahl@emory.edu
404-727-1528
Time Frame
Start Date: 2026-02-16
Estimated Completion Date: 2027-08
Participants
Target number of participants: 18
Treatments
Experimental: Adults with PKU receiving test diet and Oral stable nonradioactive isotope provision
Participants will receive amino acid tracer (Oral stable nonradioactive isotope provision) and test diet (medical food) throughout each study day, for a total of 7 study days.
Related Therapeutic Areas
Sponsors
Leads: Emory University