Effect of Oral Feeding in Infants With Pierre Robin Syndrome: A Randomized Controlled Study
This was a randomized controlled study. The infants enrolled were randomly divided into the IOE group (with Intermittent Oro-Esophageal Tube Feeding) and the PNG group (with Nasogastric Tube Feeding), all receiving systemic therapy. Before and after 4-week treatment, pulmonary infection, swallowing function, nutritional status and body weight between the two group were compared.
• meeting the diagnostic criteria for Pierre Robin sequence based on CT and X-ray examinations, combined with clinical manifestations and physical signs.
• with spontaneous vaginal birth, aged 1 to 12 months.
• with dysphagia screened by the water drinking test and further confirmed by the assessment of Dysphagia Disorders Survey (DDS), Dysphagia Severity Scale (DSS), or Schedule for Oral Motor Assessment (SOMA)
• before the treatment, the tube feeding was required and feasible after evaluation.
• stable vital signs.
• with nasogastric tubes placed before the treatment.
• sufficient human milk could be provided by the mothers of the patients (with the help of a manual suction device).