The Efficacy and Safety Study of Medical Thoracoscope Cryotherapy Combined With Standard First-line Treatment of Advanced Non-small Cell Lung Cancer and Malignant Pleural Effusion: a Multicenter, Prospective, Randomized, Controlled Clinical Trial

Status: Unknown
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study intends to investigate the efficacy and safety of medical thoracoscopic cryotherapy combined with standard first-line treatment of advanced non-small cell lung cancer with malignant pleural effusion through a randomized controlled clinical trial.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• 18-75 years old;

• Non-small cell lung cancer with pleural metastasis confirmed by histopathology or cytology;

• ECOG score 0-1;

• Cardiopulmonary function can tolerate painless thoracoscopic examination;

• Patients who underwent medical thoracoscopy for pleural effusion at first diagnosis and underwent medical thoracoscopy cryotherapy at the same time of biopsy were also included in the study. Non-small cell lung cancer was confirmed by pathological results;

• All subjects or their guardians must sign the informed consent before entering the study.

Locations
Other Locations
China
Department of Respiratory, The First Affiliated Hospital of Shandong First Medical University
RECRUITING
Jinan
Contact Information
Primary
Qian Qi, doctor
qiqianqlh@163.com
8613706380314
Time Frame
Start Date: 2022-04-06
Completion Date: 2024-12-31
Participants
Target number of participants: 141
Treatments
Experimental: Experimental group (medical thoracoscopic cryotherapy)
Active_comparator: Cisplatin/erythromycin control group (sequential intrathoracic injection of cisplatin/erythromycin)
Other: Blank control group
Only intrathoracic tube was used to drain pleural effusion, and local pleural cavity was not treated.
Sponsors
Leads: Qianfoshan Hospital

This content was sourced from clinicaltrials.gov