Can Talc Pleurodesis for Malignant Pleural Effusion be Performed on an Ambulatory Basis

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Patients with malignant pleural disease often experience a significant symptom burden and a short life expectancy. The cornerstone of their treatment is relieving breathlessness by draining fluid from around the lungs and attempting to prevent further fluid build up. Inpatient chest drainage and talc pleurodesis remains the most successful method of stopping the fluid build up but this often requires an average hospital stay of four days. This can be an inappropriate length of time for this patient group. Our study would investigate whether this treatment could be provided on an outpatient, ambulatory basis and facilitate a greater quality of life. The investigators would assess deliverability of the trial protocol and collect patient feedback to see if our patients consider it an acceptable and worthwhile intervention.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Malignant pleural effusion

• Life expectancy \>30 days

• WHO PS 1-2 (3 if due to dyspnoea)

Locations
Other Locations
United Kingdom
North Tees and Hartlepool NHS foundation trust
RECRUITING
Stockton-on-tees
Contact Information
Primary
Kevin Conroy, MBBS, FRCP
kevin.conroy@nhs.net
01642624615
Time Frame
Start Date: 2024-01-10
Estimated Completion Date: 2025-02
Participants
Target number of participants: 15
Treatments
Experimental: outpatient drain and talc pleurodesis
Patients enrolled to the trial will have a chest drain inserted and we will aim to drain to dryness and instill medical grade talc as described in the protocol
Related Therapeutic Areas
Sponsors
Leads: David Rollins

This content was sourced from clinicaltrials.gov

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