Transcranial Magnetic Stimulation to Improve Functioning in Veterans With PTSD

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Posttraumatic Stress Disorder (PTSD) is a common and serious condition affecting many Veterans. There are effective treatments for PTSD, but additional treatments are needed in order to better serve Veterans suffering from PTSD. Transcranial magnetic stimulation is one such promising treatment. It involves use of powerful magnet to stimulate the specific brain regions in Veterans with PTSD. Transcranial magnetic stimulation has been shown effective in treating depression, but currently it is unclear if it is an effective treatment for PTSD. This is a randomized clinical trial enrolling 91 Veterans with PTSD comparing the effectiveness of transcranial magnetic stimulation treatment and sham transcranial magnetic stimulation in treating PTSD. The hypothesis is that those who receive transcranial magnetic stimulation will experience improved functioning.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 19
Maximum Age: 70
Healthy Volunteers: f
View:

• Moderate to severe PTSD as determined by the CAPS within 7 days of randomization.

• Agree to have CAPS audio-recorded.

• Ability to obtain a Motor Threshold using the TMS device during screening.

• Patient eligible for VA healthcare.

• If female with childbearing potential, use of acceptable method of birth control (i.e., use of contraceptives, abstinence).

• Able to read, understand, and sign the informed consent document.

Locations
United States
Vermont
White River Junction VA Medical Center, White River Junction, VT
RECRUITING
White River Junction
Contact Information
Primary
Bradley V Watts, MD MPH
Bradley.Watts@va.gov
(802) 295-9363
Backup
Sarah L Cornelius
Sarah.Cornelius@va.gov
(802) 295-9363
Time Frame
Start Date: 2020-12-01
Estimated Completion Date: 2025-09-30
Participants
Target number of participants: 91
Treatments
Experimental: TMS
transcranial magnetic stimulation delivered to the right dorsolateral prefrontal cortex at 1 Hz
Sham_comparator: Sham
sham transcranial magnetic stimulation delivered to the right dorsolateral prefrontal cortex
Related Therapeutic Areas
Sponsors
Leads: VA Office of Research and Development

This content was sourced from clinicaltrials.gov