Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1
Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this research study is to examine the role oxidants, substances produced in the blood that can damage blood vessel function, may play in blood vessel function in healthy individuals as well as individuals with mental health disorders (posttraumatic stress disorder (PTSD) and/or generalized anxiety disorder (GAD)).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 35
Healthy Volunteers: t
View:
• apparently healthy and free of overt cardiovascular, pulmonary, or metabolic disease
• for PTSD group, a score of ≥ 33 on PCL-5 checklist
• for GAD group, a score of ≥ 10 on the GAD-7 self-report scale and \< 33 on the PCL-5 checklist
• for Healthy Control group, a score of ≤ 10 on the GAD-7 self-report scale and \< 33 on the PCL-5 checklist
Locations
United States
Virginia
Virginia Commonwealth University
RECRUITING
Richmond
Contact Information
Primary
Ryan Garten, PhD
rsgarten@vcu.edu
(804) 828-1948
Time Frame
Start Date: 2021-08-23
Estimated Completion Date: 2025-12
Participants
Target number of participants: 720
Treatments
Experimental: Antioxidant then Placebo
Subjects will ingest an antioxidant cocktail prior to their second visit and a placebo prior to third second visit
Experimental: Placebo then Antioxidant
Subjects will ingest a placebo prior to their second visit and an antioxidant cocktail prior to their third visit.
Related Therapeutic Areas
Sponsors
Leads: Virginia Commonwealth University