The Influence of Aerobic Exercise on Consolidation of Fear Extinction Learning in PTSD
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study aims to test whether aerobic exercise performed after fear extinction learning improves cognitive, physiological, and neural indices of extinction recall in a sample of trauma-exposed men and women with and without posttraumatic stress disorder (PTSD). Participants will complete a clinical intake visit (Day 0), followed by a three-day fear conditioning (day 1), fear extinction + activity (day 2), and fear extinction recall (day 3) protocol.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 64
Healthy Volunteers: t
View:
• male or female sex
• right-handed
• age 18-64
• a current diagnosis of PTSD where the index event involves interpersonal violence exposure (e.g., physical/sexual assault).
• male or female sex
• right-handed
• age 18-64
• interpersonal violence exposure (e.g., physical/sexual assault).
Locations
United States
Alabama
Wade Hall - University of Alabama
RECRUITING
Tuscaloosa
Contact Information
Primary
Kevin Crombie, PhD
kmcrombie@ua.edu
2053482684
Time Frame
Start Date: 2024-01-29
Estimated Completion Date: 2029-03
Participants
Target number of participants: 120
Treatments
Experimental: Light-intensity aerobic exercise
Experimental: Moderate-intensity aerobic exercise
Experimental: High-intensity aerobic exercise
Related Therapeutic Areas
Sponsors
Leads: University of Alabama, Tuscaloosa