Clinical Effectiveness and Implementation of Trauma-Informed Guilt Reduction Therapy Compared to Prolonged Exposure (TrIGR)

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn if receiving Trauma-Informed Guilt Reduction (TrIGR) Therapy is as effective as receiving Prolonged Exposure Therapy among veterans with PTSD and trauma related guilt. The main questions it aims to answer are: Will TrIGR be comparable to PE in terms of PTSD symptom reduction? Will it TrIGR be comparable to PE in improving functioning and reducing depression symptoms? Will it be superior in improving trauma-related guilt and shame?

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• U.S. Veterans age 18 or older who served in the military since the start of Operation Enduring Freedom/Operation Iraqi Freedom; OEF/OIF)

• meets diagnostic criteria for PTSD;

• a score of 2 or higher (true to extremely true) on feeling trauma-related guilt much or all of the time or scoring 3 or higher (very true or extremely true) on at least one guilt cognition factor (hindsight bias/responsibility, wrongdoing, or lack of justification) on the Trauma Related Guilt Inventory

• not currently receiving trauma-focused treatment such as PE or CPT

• willingness to attend psychotherapy and assessment sessions

Locations
United States
Arkansas
Little Rock Veterans Health Care System (LRVHCS)
RECRUITING
Little Rock
Louisiana
Southeast Louisiana Veterans Health Care System (SLVHCS)
RECRUITING
New Orleans
Wisconsin
William S. Middleton Memorial Hospital
RECRUITING
Madison
Contact Information
Primary
Sonya Norman, PhD
snorman@ucsd.edu
858-518-8266
Backup
Kaitlyn Panza, PhD
kaitlyn.panza@va.gov
858-552-8585
Time Frame
Start Date: 2024-12-01
Estimated Completion Date: 2027-08
Participants
Target number of participants: 158
Treatments
Experimental: trauma Informed Guilt Reduction Therapy
6 session behavioral intervention focused on trauma-related guilt, shame, and moral injury
Active_comparator: Prolonged Exposure Therapy
12 session behavioral intervention focused on PTSD symptoms
Related Therapeutic Areas
Sponsors
Collaborators: Center for Veterans Research and Education, University of Minnesota
Leads: Veterans Medical Research Foundation

This content was sourced from clinicaltrials.gov