Adaption of the STAIR-NT Trauma Intervention for Polysubstance Populations

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

During this 36-month R34 trial, eight study phases are proposed to adapt an evidence-based post traumatic stress disorder (PTSD) intervention (STAIR-NT) and layer it into a methadone maintenance treatment (MMT) program (START Treatment and Recovery centers) in New York City for use among individuals engaged in stimulant-opioid polysubstance use. The study aims to adapt STAIR-NT to a massed treatment schedule. Once an adapted protocol is complete, it will be tested for feasibility, acceptability, and short-term polysubstance and PTSD symptomology outcomes in a pilot randomized control trial (RCT) of 80 participants. Participants who screen eligible and consent will be randomized 1:1 to the adapted STAIR-NT intervention or treatment as usual (TAU) using randomization blocks of two and two and four via a computer-generated randomization sequence. Participants assigned to the intervention will receive the adapted massed delivery of STAIR-NT by trained counselors.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• must be 18 years or older,

• be a patient at the START clinic receiving methadone for treatment of opioid use disorder,

• self-report 10+ days of co-use of cocaine and illicit opioids in the past 30-days,

• meet the criteria for stimulant use disorder (cocaine type; mild, moderate or severe) and a score of 3≥ on the PC-PTSD-5.

Locations
United States
Florida
Florida State University
RECRUITING
Tallahassee
New York
START Treatment and Recovery Centers
RECRUITING
Brooklyn
NYU Langone Health
RECRUITING
New York
Contact Information
Primary
Brittany Griffin
Brittany.Griffin@nyulangone.org
646-501-3564
Backup
Amanda Bunting
Amanda.Bunting@nyulangone.org
646-501-3563
Time Frame
Start Date: 2024-10-14
Estimated Completion Date: 2026-04-30
Participants
Target number of participants: 80
Treatments
Experimental: Adapted STAIR-NT Intervention
Active_comparator: Treatment as Usual (TAU)
Related Therapeutic Areas
Sponsors
Collaborators: National Institute on Drug Abuse (NIDA)
Leads: NYU Langone Health

This content was sourced from clinicaltrials.gov