Multimodal Image Analysis and Guidance of Neuromodulation for Trauma-Related Symptoms
MAGNETS is a prospective, randomized, parallel-design, sham-controlled clinical trial of accelerated, functional magnetic resonance imaging (fMRI)-guided intermittent theta burst stimulation (iTBS) to the right dorsolateral prefrontal cortex (dlPFC) for chronic symptoms of posttraumatic stress disorder (PTSD) in a comorbid Veteran population.
• Veterans will be enrolled in this study if they:
‣ are aged 18-80;
⁃ have a documented diagnosis of PTSD with evidence of ongoing symptoms as demonstrated by score of 31 or higher on the PCL-5, a measure of posttraumatic stress symptoms;
⁃ are fluent in English (as the neuropsychological testing tools used are only available in English) and
⁃ have been on stable doses of psychotropic medications for the past month.