Onsite PTSD Treatment to Improve MOUD Outcomes: Open Pilot Trial of Stakeholder-engaged Adapted Cognitive Processing Therapy

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this open pilot trial is to learn if an adapted version of Cognitive Processing Therapy (CPT), delivered through telehealth, can treat posttraumatic stress disorder (PTSD) in adults who use syringe services programs. The main questions it aims to answer are: * Can the intervention be done in syringe services programs? * Are syringe services program clients and staff open to the intervention? * Can the intervention lower PTSD symptoms and help participants keep taking their medication for opioid use disorder (ex. Buprenorphine or methadone)? Participants will: * Attend 4-18 tele-delivered CPT sessions at the syringe services program * Complete between-session CPT practice with the support of SSP-based coaches * Meet with research staff monthly to complete surveys of their PTSD symptoms, drug use, and mental health

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Over the age of 18

• Regular syringe services program attendance (ex. at least 4 visits in the past month)

• Meeting DSM-5 opioid use disorder criteria

• Having been prescribed a medication for opioid use disorder in the past 30 days at the time of screening

• Criterion A event as measured by the Life Events Checklist for DSM-5 (LEC-5)

• PTSD symptoms at the level of a PTSD diagnosis as evidenced by a score of 31 or greater on the PTSD Checklist for DSM-5 (PCL-5)

• Ability to understand English

• Consent to have assessment interviews audio recorded and teletherapy sessions video recorded for research purposes

• Ability to provide informed consent

Locations
United States
New York
OnPoint
RECRUITING
New York
Contact Information
Primary
Teresa Lopez-Castro, PhD
tlopezcastro@ccny.cuny.edu
646-745-7123
Backup
Aaron D Fox, MD
adfox@montefiore.org
718-920-7173
Time Frame
Start Date: 2025-11-17
Estimated Completion Date: 2026-09
Participants
Target number of participants: 15
Treatments
Experimental: Adapted Cognitive Processing Therapy
Participants will receive 4-18 sessions of telehealth-delivered Cognitive Processing Therapy (CPT) adapted for people who use syringe services programs. Participants will attend the 50-minute CPT sessions in a private space within the syringe services program.
Related Therapeutic Areas
Sponsors
Collaborators: National Institute on Drug Abuse (NIDA), Albert Einstein College of Medicine
Leads: The City College of New York

This content was sourced from clinicaltrials.gov