Post-Traumatic Stress Disorder (PTSD) Clinical Trials

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Neural Mechanisms of Floatation-REST Therapy for Post-Traumatic Stress Symptoms in Frontline Healthcare Workers

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY

This early-stage pilot trial aims to examine the feasibility, tolerability, and safety of Floatation-REST, or Reduced Environmental Stimulation Therapy via floatation in frontline healthcare workers, first responders, and emergency medical personnel who experience post-traumatic stress symptoms.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 64
Healthy Volunteers: f
View:

• Work-related post-traumatic stress dysfunction as measured by either of the following inclusion pathways:

• (A) PTSS Pathway: PCL-5 greater than or equal to 20, OR meets criteria for full or partial PTSD on the MINI International Neuropsychiatric Interview 7 (DSM-V) (Criteria A + at least 2 B-E Criteria) OR (B) Functionally Anchored Pathway: evidence of work-related trauma exposure on the MINI International Neuropsychiatric Interview 7 (DSM-V) (Criterion A) or Life Events Checklist-5, and at least one of the following: Moral Injury and Distress Scale greater than or equal to 27, Sheehan Disability Scale greater than or equal to 5 on at least 1 of the 3 subscales, high or very high level of perceived stress (measured by PhenX Perceived Stress Scale greater than or equal to 16).

• First responder or other emergency medical personnel

• Ability to read, speak and understand English

• Capable of providing consent

Locations
United States
Oklahoma
Laureate Institute for Brain Research
RECRUITING
Tulsa
Contact Information
Primary
Adrienne Taren, MD, PhD
ataren@laureateinstitute.org
918-340-4116
Backup
Emily M Choquette, PhD
echoquette@laureateinstitute.org
918-240-2583
Time Frame
Start Date: 2026-06-10
Estimated Completion Date: 2026-12
Participants
Target number of participants: 15
Treatments
Experimental: Floatation-REST
Participants will float supine in a shallow pool for two one-hour sessions approximately seven days apart.
Active_comparator: Documentary Condition
Participants will watch two one-hour documentaries in a relaxing environment approximately seven days apart.
Related Therapeutic Areas
Sponsors
Leads: Laureate Institute for Brain Research, Inc.

This content was sourced from clinicaltrials.gov