Evaluation of the Effectiveness of Eye-tracking Assisted Attentional Bias Reduction Therapy on Reducing Symptoms of Post-traumatic Stress Disorder

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Post-traumatic stress disorder (PTSD) is associated with an attentional bias towards negative stimuli, which is supposed to contribute to the development and the maintenance of the disorder. We recently showed using eye-tracking evidenced two types of AB towards negative stimuli: a physiological AB found both in healthy and individual with PTSD, characterized by a stronger initial attentional engagement towards negative stimuli compared to neutral stimuli, as revealed by longer first fixation duration dwell time on negative pictures than on neutral pictures; a pathological bias observed only in individuals with PTSD and characterized by an heightened sustained attention towards negative stimuli once detected, which further increases with prolonged exposure. The present study aimed at assessing the effectiveness of an eye-tracking assisted attentional bias reduction therapy, targeting specifically the pathological bias on the reduction of PTSD symptoms

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:

• Understanding and able to express themselves in French

• Giving informed consent, by dating and signing the study participation form

• Having health insurance coverage

• Normal or corrected to normal vision and hearing

• DSM-5 PTSD criteria, assessed using the CAPS and PCL-5

Locations
Other Locations
France
Hôpital Fontan 2
RECRUITING
Lille
Contact Information
Primary
Guillaume VAIVA, MD,PhD
guillaume.vaiva@chru-lille.fr
0320445962
Backup
Fabien D'HONDT, PhD
fabien.d-hondt@univ-lille.fr
Time Frame
Start Date: 2024-02-02
Estimated Completion Date: 2029-02-02
Participants
Target number of participants: 140
Treatments
Experimental: patients with a PTSD receiving ACTo and prolonged exposure therapy.
Sham_comparator: patients with PTSD receiving ACT and prolonged exposure therapy.
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Lille

This content was sourced from clinicaltrials.gov