Transcutaneous Vagal Nerve Stimulation in Veterans With Posttraumatic Stress Disorder
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study effects the effects of transcutaneous cervical vagal nerve stimulation (tcVNS) or a sham control on brain, physiology, and PTSD symptoms in Veterans with posttraumatic stress disorder (PTSD). Veterans undergo brain imaging and physiological measures in conjunction with traumatic scripts before and after three months of twice daily treatment with tcVNS or sham stimulation at home.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:
• Veterans between the ages of 18 and 75 will be included with a diagnosis of PTSD based on DSM-5 criteria
Locations
United States
Georgia
Atlanta VA Medical and Rehab Center, Decatur, GA
RECRUITING
Decatur
Contact Information
Primary
Doug J Bremner, MD
James.Bremner@va.gov
(404) 712-9569
Time Frame
Start Date: 2022-10-01
Estimated Completion Date: 2026-11-17
Participants
Target number of participants: 80
Treatments
Experimental: tcVNS
Stimulation twice daily with transcutaneous Vagal Nerve Stimulation (tcVNS)
Active_comparator: sham
stimulation with sham
Related Therapeutic Areas
Sponsors
Leads: VA Office of Research and Development