Pilot Feasibility Proposal to Adapt Trauma-focused Psychodynamic Psychotherapy (TFPP) for PLWH and PTSD

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

People living with HIV (PLWH) have a higher rate of post-traumatic stress disorder (PTSD) diagnosis than the general population. Comorbid PTSD is also associated with negative HIV-related health outcomes. Unfortunately, little outcome research has examined the usefulness of PTSD treatments for PTSD. This pilot study adapts for PLWH a non-exposure based psychotherapy for PTSD focused on reflecting on one's emotions and relationships and understanding and working through how trauma may have disrupted them. The study team is interested in better understanding the needs of PLWH with PTSD, learning whether PLWH with PTSD find this treatment acceptable and helpful, and beginning to understand the relationship between HIV-related health factors (e.g., inflammation and stress biology) and PTSD, and how these health factors may improve during treatment.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Diagnosis of DSM-5 defined PTSD, per the Clinician Administered PTSD Scale \& CAPS-5 total severity score greater than or equal to 25

• HIV diagnosis (by medical records or HIV testing)

• Stable psychiatric/psychotropic medication for \>=2 months and ongoing during treatment

Locations
United States
New York
Albert Einstein College of Medicine
RECRUITING
The Bronx
Contact Information
Primary
John R Keefe, PhD
john.keefe@einsteinmed.edu
703-981-7184
Backup
Barbara L Milrod, MD
bmilrod@montefiore.edu
917-593-1377
Time Frame
Start Date: 2024-04-26
Estimated Completion Date: 2026-04
Participants
Target number of participants: 20
Treatments
Experimental: Trauma-focused psychodynamic psychotherapy
Twice-weekly psychotherapy for 24 sessions
Sponsors
Collaborators: National Institute of Allergy and Infectious Diseases (NIAID), American Psychoanalytic Association
Leads: Montefiore Medical Center

This content was sourced from clinicaltrials.gov