Comparative Acute Effects of R-MDMA and S-MDMA in Healthy Participants
Racemic ±3,4-methylenedioxymethamphetamine (MDMA) is a psychoactive substance and prototypical empathogen acutely inducing feelings of heightened mood, empathy, trust and closeness to others. These acute subjective effects of MDMA may be helpful to assist psychotherapy and MDMA has been investigated in phase 3 trials as a possible treatment in post-traumatic stress disorder.
• Age between 18 and 65 years
• Good understanding of the German language
• Understanding of procedures and risks associated with the study
• Willing to adhere to the protocol and signing of the consent form
• Willing to refrain from the consumption of illicit psychoactive substances during the study
• Willing not to operate heavy machinery within 48 h after administration of a study substance (including driving a car)
• Willing to use effective birth-control throughout study participation.
• Body mass index 18 - 34.9 kg/m2