Find Post-Traumatic Stress Disorder (PTSD) Clinical Trials Near You
Adaptive Interventions to Improve Posttraumatic Stress Disorder (PTSD) Treatment Access, Engagement, and Effectiveness in Routine Care
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Less than 20% of people with PTSD receive any treatment. This study extends a program of research by the investigator focused on developing adaptive (stepped) interventions for PTSD. The adaptive intervention sequences a digital mental health intervention (DMHI) and brief trauma- and skills-focused treatments for PTSD. The selected treatments are brief and scalable and less burdensome to systems of care. These treatments are: web-administered Skills Training in Affective and Interpersonal Regulation (webSTAIR), Brief STAIR, and Written Exposure Therapy (WET).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
⁃ Assessed at pre-screening
• Boston Medical Center primary care patient
• At least 18 years of age
• Access to computer or mobile device
• Able to receive treatments in English or Spanish
• Able to read at 4th grade level
⁃ Assessed at baseline
• Endorsement of Criterion A trauma using the Life Events Checklist for the DSM-5 (LEC-5), assessed at baseline
• PTSD diagnosis, confirmed by the Clinician-Administered PTSD Scale for the DSM-5 (CAPS-5) assessed at baseline
• Clinically appropriate for outpatient level of care
• Stable on psychotropic medication for \>4 weeks
Locations
United States
Massachusetts
Boston Medical Center
RECRUITING
Boston
Contact Information
Primary
Sarah Valentine, PhD
sarah.valentine@bmc.org
857 264 1102
Time Frame
Start Date:2026-03-12
Estimated Completion Date:2029-06
Participants
Target number of participants:428
Treatments
Active_comparator: webSTAIR, webSTAIR to WET
First, offer skills-focused digital mental health intervention (DMHI); then switch to clinician-administered trauma-focused behavioral treatment for nonresponders and continue skills-focused DMHI for responders.
Active_comparator: webSTAIR+coaching, webSTAIR+coaching to WET
First, offer skills-focused DMHI plus community health worker (CHW) coaching; then add clinician-administered trauma-focused behavioral treatment for nonresponders and continue skills-focused DMHI plus CHW coaching for responders.
Active_comparator: webSTAIR, webSTAIR to Brief STAIR
First, offer skills-focused DMHI; then add clinician-administered skills-focused behavioral treatment for nonresponders and continue skills-focused DMHI for responders.
Active_comparator: webSTAIR+coaching, websTAIR+coaching to Brief STAIR
First, offer skills-focused DMHI plus CHW coaching; then add clinician-administered skills-focused behavioral treatment for nonresponders and continue skills-focused DMHI plus CHW coaching for responders.