Postpartum Depression Clinical Trials

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Postpartum Education Via Artificial Intelligence for Recovery and Loneliness (PEARL): A Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn whether a postpartum chatbot powered by generative artificial intelligence (genAI) can help new mothers get better pelvic floor health information and feel less lonely after childbirth. The main questions this study aims to answer are: * Does using the chatbot improve postpartum pelvic floor health knowledge? * Does using the chatbot help reduce feelings of loneliness during the postpartum period? * Does using the chatbot impact pelvic floor symptoms? Researchers will compare standard postpartum care to standard care plus the chatbot. Participants will: Be assigned by chance (like flipping a coin) to standard postpartum care with or without access to the chatbot. If in the chatbot group, participants will receive education and support via the chatbot over a 4-week period. Both groups will complete questionnaires to measure their pelvic floor knowledge, pelvic floor symptoms, feelings of loneliness, depression, infant bonding, perceived social support, adverse childhood experiences, and peri-traumatic distress. The chatbot was created by urogynecology experts in collaboration with UC San Diego computer science and biomedical informatics researchers. The chatbot is designed to give new mothers personalized, evidence-based information and support in real time.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:

• Has the capacity to provide informed consent

• Stated willingness to comply with all study procedures and availability for the duration of the study

• Postpartum persons, aged \>18 years old

• Primiparous

• Vaginal or cesarean delivery

• English Speaking

• Internet access and proficiency of internet access

• Access to a smartphone

• Postpartum 2-6 weeks

Locations
United States
California
University of California San Diego
RECRUITING
La Jolla
Contact Information
Primary
Alexandra C Nutaitis, DO
anutaitis@health.ucsd.edu
858-657-7344
Backup
Cecile Ferrando, MD, MPH
cferrando@health.ucsd.edu
(858) 657-1238
Time Frame
Start Date: 2026-01-08
Estimated Completion Date: 2026-11-01
Participants
Target number of participants: 130
Treatments
Active_comparator: Standard postpartum care
Standard postpartum care
Experimental: Generative AI Chatbot Intervention
Generative AI Chatbot Intervention
Related Therapeutic Areas
Sponsors
Leads: University of California, San Diego

This content was sourced from clinicaltrials.gov