Noninvasive Neuromodulation of a Novel Cerebellar Satiety Circuit in Prader-Willi Syndrome
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study hyperphagia and satiety in Prader-Willi syndrome. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study, the investigators will be stimulating the brain to learn more about how TMS might improve hyperphagia in Prader-Willi syndrome.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 64
Healthy Volunteers: f
View:
• Diagnosis of Prader-Willi syndrome
Locations
United States
Massachusetts
McLean Hospital
RECRUITING
Belmont
Contact Information
Primary
Laura Holsen, PhD
lholsen@bwh.harvard.edu
617-525-8772
Time Frame
Start Date: 2023-09-01
Estimated Completion Date: 2025-10
Participants
Target number of participants: 20
Treatments
Experimental: Active cerebellum rTMS
Cerebellar targeted iTBS, once daily, one week
Related Therapeutic Areas
Sponsors
Leads: Brigham and Women's Hospital
Collaborators: Foundation for Prader-Willi Research