A Phase 3, Multicenter, Open-Label Extension Study to Assess the Safety and Efficacy of ARD-101 in Patients With Prader-Willi Syndrome

Status: Recruiting
Location: See all (36) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

The goal of this clinical trial is to learn if ARD-101 works to treat hyperphagia-related behavior in patients with Prader-Willi syndrome (PWS) when used in a long term setting. It will also teach us about the safety of ARD-101. The main questions it aims to answer are: What medical problems do participants have when taking ARD-101 in a long term setting Does ARD-101 improve the total score of the HQCT-9 (hyperphagia questionnaire for clinical trials, 9 questions)? Eligible participants will: Have completed treatment on the AVK-101-301 study through Week 12/End of Treatment Take ARD-101 every day for up to 12 months. Visit the clinic at Months 1, 3, 6 and 12 during dosing and then have tele-visits at Week 2, Months 3 and 9, then 4 weeks after stopping the ARD-101. Patients/Caregivers will keep a daily diary.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 13
Healthy Volunteers: f
View:

• Patients who have completed treatment on Aardvark Therapeutics clinical study AVK-101-301

Locations
United States
Alabama
Children's of Alabama
NOT_YET_RECRUITING
Birmingham
California
Stanford Children's Health Specialty Services
NOT_YET_RECRUITING
Palo Alto
Rady Children's Hospital
NOT_YET_RECRUITING
San Diego
Colorado
Children's Hospital Colorado
NOT_YET_RECRUITING
Denver
Delaware
Nemours Children's Clinic Wilmington
NOT_YET_RECRUITING
Wilmington
Florida
UF Shands Children's Hospital
NOT_YET_RECRUITING
Gainesville
Georgia
Emory University School of Medicine
NOT_YET_RECRUITING
Atlanta
Minnesota
University of Minnesota Masonic Children's Hospital
NOT_YET_RECRUITING
Minneapolis
New York
Maimonides Medical Center
NOT_YET_RECRUITING
Brooklyn
NYU Langone Children's Ambulatory Care Center
RECRUITING
Mineola
Tennessee
Vanderbilt University Medical Center
NOT_YET_RECRUITING
Nashville
Texas
Cook Children's Medical Center
NOT_YET_RECRUITING
Fort Worth
Washington
Seattle Children's Hospital
NOT_YET_RECRUITING
Seattle
Other Locations
Australia
Queensland Children's Hospital
NOT_YET_RECRUITING
South Brisbane
The Children's Hospital at Westmead
NOT_YET_RECRUITING
Westmead
France
CHU d'Angers
NOT_YET_RECRUITING
Angers
AP-HP - Hôpital de la Pitié Salpétrière
NOT_YET_RECRUITING
Paris
AP-HP - Hôpital universitaire Necker-Enfants malades
NOT_YET_RECRUITING
Paris
CHU de Toulouse- Hôpital de Rangueil
NOT_YET_RECRUITING
Toulouse
CHU de Toulouse-Hôpital Des Enfants
NOT_YET_RECRUITING
Toulouse
Italy
Azienda Ospedaliero Universitaria A Meyer - INCIPIT - PIN
NOT_YET_RECRUITING
Florence
Ospedale San Raffaele S.r.l. - PPDS
NOT_YET_RECRUITING
Milan
Ospedale Pediatrico Bambino Gesù IRCCS
NOT_YET_RECRUITING
Rome
Republic of Korea
Inha University Hospital
NOT_YET_RECRUITING
Incheon
Samsung Medical Center
NOT_YET_RECRUITING
Seoul
Ajou University Hospital
NOT_YET_RECRUITING
Suwon
Romania
Institutul National de Endocrinologie C. I. Parhon
NOT_YET_RECRUITING
Bucharest
National University Hospital for Children's Neurorehabilitation Dr. Nicolae Robanescu
RECRUITING
Bucharest
Spitalul Clinic de Urgenta Sfantul Spiridon
NOT_YET_RECRUITING
Iași
Spain
Hospital Universitario Vall d'Hebron - PPDS
NOT_YET_RECRUITING
Barcelona
Hospital Universitario 12 de Octubre
NOT_YET_RECRUITING
Madrid
Corporacio Sanitaria Parc Tauli
NOT_YET_RECRUITING
Sabadell
United Kingdom
Fulborn Hospital
NOT_YET_RECRUITING
Cambridge
Royal Hospital for Children (Glasgow) - PPDS - PIN
NOT_YET_RECRUITING
Glasgow
Leicester Royal Infirmary
NOT_YET_RECRUITING
Leicester
The Royal London Hospital
NOT_YET_RECRUITING
London
Contact Information
Primary
Vanessa Wong
Info@AardvarkTherapeutics.com
858-225-7696
Time Frame
Start Date: 2024-07-23
Estimated Completion Date: 2027-04
Participants
Target number of participants: 90
Treatments
Experimental: ARD-101
(Open-label)
Related Therapeutic Areas
Sponsors
Leads: Aardvark Therapeutics, Inc.

This content was sourced from clinicaltrials.gov