Open Lung Maneuvers During High Frequency Oscillatory Ventilation in Extremely Preterm Infants - a Single Center Randomized Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
To assess whether stepwise oxygenation-guided lung recruitment at regular intervals reduces the oxygen saturation index (OSI = Mean Airway Pressure × Fraction of inspired Oxygen × 100 / peripheral Oxygen Saturation, OSI = MAPxFiO2x100/SpO2) averaged over high frequency oscillation ventilation (HFOV) time in extremely preterm infants.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 1 month
Healthy Volunteers: f
View:
• born below 28 weeks of gestational age
• not older than 29 weeks of postmenstrual age
• receive HFOV
Locations
Other Locations
Austria
Medical University of Vienna
RECRUITING
Vienna
Contact Information
Primary
Tobias Werther
tobias.werther@meduniwien.ac.at
+4314040032320
Time Frame
Start Date: 2020-02-25
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 36
Treatments
Experimental: Intervention
lung recruitment maneuvers performed every twelve hours during HFOV
No_intervention: Control
no regular lung recruitment maneuvers during HFOV
Related Therapeutic Areas
Sponsors
Leads: Medical University of Vienna