Womb Recordings and Respiratory Control Maturation in Neonates
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The aim of this proposal is to characterize the acute effect of early postnatal sound exposure on neuronal maturation of the respiratory control regions of the brain in preterm infants.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 7 days
Maximum Age: 1 month
Healthy Volunteers: f
View:
• preterm infants 29-33 weeks gestational age at birth
• 34 weeks corrected age
• off respiratory support \>1.5 lpm
Locations
United States
Ohio
University Hospitals Cleveland Medical Center
RECRUITING
Cleveland
Contact Information
Primary
Cynthia Bearer, MD
Cynthia.Bearer@UHhospitals.org
216 844-3387
Time Frame
Start Date: 2022-09-16
Estimated Completion Date: 2025-11
Participants
Target number of participants: 34
Treatments
Other: Ambient noise followed by Womb sound
At 34 weeks corrected age, preterm infants (29-33 weeks gestational age at birth), who are off respiratory support \>1.5 lpm, will be exposed to alternating 6-hour periods of a recording of ambient noise followed by commercially available womb sounds over a 24-hour period for a combined total of 12 hours of womb sounds and 12 hours of ambient noise.
Other: Womb sound recordings followed by ambient noise
At 34 weeks corrected age, preterm infants (29-33 weeks gestational age at birth), who are off respiratory support \>1.5 lpm, will be exposed to alternating 6-hour periods of a recording of commercially available womb sounds followed by ambient noise over a 24-hour period for a combined total of 12 hours of womb sounds and 12 hours of ambient noise.
Related Therapeutic Areas
Sponsors
Leads: Case Western Reserve University