Antenatal Dexamethasone for Late Preterm Deliveries: a Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1
SUMMARY

The goal of this clinical trial is to compare dexamethasone in late preterm deliveries. The main questions it aims to answer are: Does antenatal dexamethasone reduce the need for respiratory support in late preterm infants? Does antenatal dexamethasone reduce neonatal morbidities and mortality? Does antenatal dexamethasone reduce admission to Neonatal Intensive Care Unit and length of hospital stay? Participants will be allocated into 2 groups: intervention with dexamethasone IM and control (standard care). Investigators will compare these two groups to see if antenatal dexamethasone reduces the need for respiratory support in late preterm infants, neonatal morbidities and mortality, admission to NICU and length of hospital stay.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: f
View:

• 34+0/7 to 36+6/7 weeks

• Expected preterm delivery for any indications in the next 7 days.

Locations
Other Locations
Viet Nam
Danang HOspital for Women and Children
RECRUITING
Da Nang
Contact Information
Primary
Chau Le, PhD
lhmchau@dhktyduocdn.edu.vn
+84905983797
Time Frame
Start Date: 2023-08-25
Estimated Completion Date: 2024-04-30
Participants
Target number of participants: 294
Treatments
Experimental: Dexamethasone group
The intervention is antenatal dexamethasone. Participants in the intervention group will be given a course of four intramuscular injections of dexamethasone 6 mg (1.2 milliliter), 12 hours apart.
No_intervention: Control group
Participants in the control group will be received standard care.
Related Therapeutic Areas
Sponsors
Leads: Chulalongkorn University

This content was sourced from clinicaltrials.gov