Post-Extubation Assessment of Clinical Stability in Extremely Preterm Infants: the PEACE Feasibility Study
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Device
Study Type: Observational
SUMMARY
This is an observational, proof-of-concept, feasibility study that aims to evaluate the feasibility of a monitoring system that integrates clinical data, high-resolution waveforms from the bedside monitor, regional oxygenation (via cerebral and splanchnic near-infrared spectroscopy), and regional ventilation (via electrical impedance tomography) from 20 extremely low birth weight infants at high-risk of reintubation.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 6 months
Healthy Volunteers: f
View:
• Birth weight \< 1000g and gestational age \< 28+0 weeks,
• Received mechanical ventilation within the first 72h of life,
• Undergoing their first planned extubation within the first 6 weeks of life.
Locations
Other Locations
Canada
Centre Hospitalier Universitaire Sainte-Justine
RECRUITING
Montreal
McGill University Health Center
RECRUITING
Montreal
Contact Information
Primary
Wissam Shalish, MD, PhD
wissam.shalish@mcgill.ca
+1(514) 4124452
Time Frame
Start Date: 2024-10-29
Estimated Completion Date: 2026-01-31
Participants
Target number of participants: 20
Treatments
20 extremely low birth weight infants
In addition to the standard care, all participants will be monitored using an extra oxygen saturation probe, two near infrared spectroscopy sensors, and an electrical impedance tomography belt. Data will be continuously collected from extubation to 168 hours postextubation
Related Therapeutic Areas
Sponsors
Leads: McGill University Health Centre/Research Institute of the McGill University Health Centre
Collaborators: St. Justine's Hospital