Evaluation of Urinary Biomarkers Trend in Preterm Very Low Birth Weight Infants: Influence of Clinical and Therapeutic Factors
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The purpose of this study is to define the temporal patterns of urinary biomarkers (CysC, EGF, KIM-1, NGAL, β2-Microglobulin, OPN, and MOD) in the first two weeks of life in preterm and/or very low birth weight (VLBW) infants in relation to the effect of specific factors (hsPDA, prenatal Doppler alterations) and drug therapies. Another objective is then to evaluate the predictivity of these biomarkers with respect to the occurrence of renal damage in preterm infants and possible cut-off values
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:
• Gestational age \<32 weeks or birth weight \<1500 g;
• Admission at birth to the Neonatal Intensive Care Unit of the IRCCS A.O.U. of Bologna Policlinico di S. Orsola;
• Obtaining informed consent from parents/legal representatives.
Locations
Other Locations
Italy
IRCCS Azienda Ospedaliero-Universitaria di Bologna
RECRUITING
Bologna
Contact Information
Primary
Francesca Vitali, MD
francesca.vitali@aosp.bo.it
+390512144463
Time Frame
Start Date: 2022-12-07
Estimated Completion Date: 2025-06-15
Participants
Target number of participants: 78
Related Therapeutic Areas
Sponsors
Leads: IRCCS Azienda Ospedaliero-Universitaria di Bologna