Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause: a Prospective Monocentric Study (CAP-TTR)
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
To investigate to what extent chronic axonal length-dependent polyneuropathy (CAP) and/or small-fiber neuropathy (SFN) is part of early non-cardiac manifestations of wild-type TTR cardiac amyloidosis (wtTTR-CA). Consequently, explore whether this could ultimately lead to faster diagnosis and clinical outcome of wild-type TTR cardiac amyloidosis (wtTTR-CA).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: f
View:
• Patients with chronic axonal length-dependent polyneuropathy (CAP) and/or small-fiber neuropathy (SFN) without well-defined etiology.
• Age: \>= 60 years
• Male and female gender
• Written informed consent
Locations
Other Locations
Belgium
UZ Brussel
RECRUITING
Jette
Contact Information
Primary
Véronique Bissay, MD,Phd
veronique.bissay@uzbrussel.be
+32 2 477 68 01
Time Frame
Start Date: 2023-07-28
Estimated Completion Date: 2026-06-01
Participants
Target number of participants: 150
Treatments
Other: 1 arm including patients with CAP and/or SFN
1 arm including patients with chronic axonal length-dependent polyneuropathy and/or small-fiber neuropathy.~All participants will be screened with ECG and echocardiography. All participants will be asked to complete questionnaires about there polyneuropathy and cardiological symptoms.
Related Therapeutic Areas
Sponsors
Leads: Universitair Ziekenhuis Brussel