Prostate Cancer Clinical Trials

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Cognitive Versus Image Guided Fusion Transrectal Prostatic Biopsy for the Detection of Prostate Cancer

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this study is to compare two different prostate biopsy techniques used to detect prostate cancer. These techniques are cognitive-targeted biopsy (CTB) and magnetic resonance imaging-ultrasound fusion-targeted transrectal biopsy (FTB). Both methods aim to improve the accuracy of prostate cancer detection by targeting suspicious areas identified on prostate imaging. This study will compare how accurately each technique detects prostate cancer, the pathological findings obtained from each biopsy method, and how operator performance may influence the procedure. The information gained from this study may help improve prostate cancer diagnosis and guide future biopsy practices.

Eligibility
Participation Requirements
Sex: Male
Healthy Volunteers: f
View:

• Biopsy-naïve patients

• Prostate-specific antigen level between 4 and 20 ng/mL

• Multiparametric Magnetic Resonance Imaging Prostate Imaging-Reporting and Data System score 4 or 5

Locations
Other Locations
Egypt
Menoufia university hospital urology department
RECRUITING
Shibīn Al Kawm
Menoufia university hospital urology department
NOT_YET_RECRUITING
Shibīn Al Kawm
Contact Information
Primary
Mahmoud A Wahbah, MASTER
mwahbah4@gmail.com
00201015684868
Time Frame
Start Date: 2025-12-28
Estimated Completion Date: 2026-08-05
Participants
Target number of participants: 80
Treatments
Experimental: Sequential cognitive-targeted biopsy followed by fusion-targeted biopsy
Participants will undergo a cognitive-targeted prostate biopsy followed immediately by a fusion-targeted prostate biopsy during the same session. Each participant will receive both biopsy techniques sequentially, allowing within-subject comparison. Participants will be assigned to one of two surgeons using a blinded randomization process; however, all participants will receive the same intervention protocol.
Related Therapeutic Areas
Sponsors
Leads: Menoufia University

This content was sourced from clinicaltrials.gov