MRI Assessment of Pulmonary Edema in Acute Heart Failure

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

Researchers are testing a more accurate way to measure how much fluid is in the lungs (also called pulmonary edema, or increased lung water) in people with Heart Failure (HF) using MRI (Magnetic Resonance Imaging). There is little known about the exact level of lung water in patients with AHF or how these levels change from the time of hospital admission to discharge. The purpose of this research study is to measure the lung water in patients hospitalized for HF, to determine the change in lung water over the course of hospitalization and treatment, and to find out if lung water levels can predict if patients are higher or lower risk for returning to the hospital or dying from heart failure.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• 18 years of age or older and willing/able to provide informed consent

• patients being treated for acute heart failure (including those patients with both reduced and preserved ejection fraction)

• patients receiving medical therapy for pulmonary edema by current standard of care (including oral or IV diuretics)

• patients identified within 48 hours of initiation of medical therapy for pulmonary edema, defined as the time of first diuretic (IV or PO) or escalation of existing diuretic therapy administered within the ED or hospital

Locations
Other Locations
Canada
University of Alberta
ACTIVE_NOT_RECRUITING
Edmonton
University of Ottawa Heart Institute
RECRUITING
Ottawa
Contact Information
Primary
Ian Paterson, MD
DPaterson@ottawaheart.ca
613-696-7267
Backup
Poppy MacPhee, RN, BScN
pmacphee@ottawaheart.ca
613-696-7000
Time Frame
Start Date: 2019-01-02
Estimated Completion Date: 2026-06-01
Participants
Target number of participants: 300
Treatments
Single Arm
Related Therapeutic Areas
Sponsors
Collaborators: Canadian Institutes of Health Research (CIHR)
Leads: University of Alberta

This content was sourced from clinicaltrials.gov