Multi-Centre Cluster-Randomized Implementation of Canadian Syncope Risk Score Based Practice Recommendations for Emergency Department Syncope Management

Status: Recruiting
Location: See all (15) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Syncope is a common reason for emergency department (ED) presentation. While often benign, some patients have serious and life-threatening underlying causes, both cardiac and non-cardiac, which may or may not be apparent at the time of the initial ED assessment. Identifying which patients will benefit from further investigation, ongoing monitoring and/or hospital admission is essential to reduce both adverse outcomes and high costs. The research team has spent over a decade developing the evidence base for a risk stratification tool directed at optimizing the accuracy of ED decisions: the Canadian Syncope Risk Score (CSRS). This tool is now ready for the final phase of its introduction into clinical practice, namely a robust, multicentre implementation trial of the CSRS-based practice recommendations to demonstrate its real-world effectiveness. These recommendations, if applied, could lead to reduction in hospitalization with only 6% of high-risk patients requiring hospitalization, shorter ED lengths of stay for the 76% of ED syncope patients who are at low risk for 30-day serious outcomes, and more standardized disposition decisions, specifically discharge of 18% of medium-risk patients after appropriate discussion. Hence, the investigators hypothesize that an important reduction in hospitalization and ED disposition time can be achieved by implementing the CSRS-based recommendations with potential improvements in patient safety. The overall objective of this study is to evaluate the effectiveness of the knowledge translation (KT) of the CSRS-based practice recommendations in multiple Canadian EDs using a stepped wedge cluster randomized trial (SW-CRT) on health care efficiency and patient safety.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• ED physicians involved in ED syncope care

• Non-ED physicians involved in ED syncope care

• Physician's delegates involved in ED syncope care

• Patients who are adults (aged \> 18 years)

• Patients who present to the ED within 24 hours of syncope.

Locations
Other Locations
Canada
Foothills Medical Centre
RECRUITING
Calgary
Health Sicence North
RECRUITING
Greater Sudbury
Hawkesbury and District General Hospital
RECRUITING
Hawkesbury
London Health Sciences Centre
RECRUITING
London
Jewish General Hospital
RECRUITING
Montreal
Royal Victoria Hospital & Montreal General Hospital
RECRUITING
Montreal
North Bay Regional Health Centre
RECRUITING
North Bay
Centre hospitalier de l'Université Laval
RECRUITING
Québec
Hôpital de L'Enfant-Jésus
RECRUITING
Québec
Hotel Dieu Hospital of Lévis
RECRUITING
Québec
Thunder Bay Regional Health Sicences Centre
RECRUITING
Thunder Bay
University Health Network
RECRUITING
Toronto
Niagara Health
RECRUITING
Welland
Winchester District Memorial Hospital
RECRUITING
Winchester
St. Boniface Hospital
RECRUITING
Winnipeg
Contact Information
Primary
Iris Nguyen, BSc
pnguyen@ohri.ca
6137985555
Time Frame
Start Date: 2023-09-18
Estimated Completion Date: 2026-03-01
Participants
Target number of participants: 14400
Treatments
Other: CSRS practice recommendation
Knowledge translation of the Canadian Syncope Risk Score (CSRS) based practice recommendations
Related Therapeutic Areas
Sponsors
Leads: Ottawa Hospital Research Institute

This content was sourced from clinicaltrials.gov