Pulmonary Hypertension Clinical Trials

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Pulmonary Hypertension (PH) Biorepository for Translational Research

Status: Recruiting
Location: See all (3) locations...
Study Type: Observational
SUMMARY

Background: Pulmonary hypertension (PH) is high blood pressure in the blood vessels of the lungs. It can lead to heart failure and death if not treated. Researchers want to create a repository of blood samples and health information collected from people with PH. They hope to use this information to find better ways to diagnose and treat PH.

Objective: To collect blood samples and health information from people suspected of or diagnosed with PH.

Eligibility: People aged 18 years and older who have or may have PH.

Design: Researchers will collect information from participants medical records. Participants will have blood drawn from a vein. About 3 tablespoons will be collected during the study visit. The visit will last about 1 hour. Participants may choose to provide new blood samples at follow-up visits. Updated medical information may also be collected. Participants may continue to participate as long as the study is ongoing. Participants may opt out of providing new blood samples but remain in the study. All study samples will be stored at the National Institutes of Health. Health information will be stored in secure databases.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 100
Healthy Volunteers: f
View:

• Provision of signed and dated informed consent form

• Males and females aged \>=18 years old

• Suspected of or diagnosed with PH

• Able to understand and willing to sign a written informed consent document

Locations
United States
Maryland
University of Maryland Medical Center at Baltimore (UMB)
NOT_YET_RECRUITING
Baltimore
National Institutes of Health Clinical Center
RECRUITING
Bethesda
Virginia
INOVA Fairfax Hospital
NOT_YET_RECRUITING
Falls Church
Contact Information
Primary
Michael A Solomon, M.D.
msolomon@cc.nih.gov
(301) 496-9320
Time Frame
Start Date: 2026-10-19
Estimated Completion Date: 2036-06-01
Participants
Target number of participants: 1000
Treatments
Group 1 (suspected of or diagnosed)
Pulmonary Arterial Hypertension, PAH
Group 2 (suspected of or diagnosed)
PH due to left heart disease
Group 3 (suspected of or diagnosed)
PH due to lung diseases and/or hypoxia
Group 4 (suspected of or diagnosed)
PH due to thromboembolic disease
Group 5 (suspected of or diagnosed)
PH with unclear or multifactorial mechanisms
Sponsors
Leads: National Institutes of Health Clinical Center (CC)

This content was sourced from clinicaltrials.gov