Comparative Study Between Inhaled and Intravenous Milrinone in Patients With Severe Pulmonary Hypertension Undergoing Cardiac Surgery
Who is this study for? Patients with Pulmonary Hypertension Due to Left Heart Disease
What treatments are being studied? Milrinone
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
The investigator compared difference between inhaled and intravenous milirinone in patiens with severe pulmonary hypertension undergoing cardiac surgery
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients scheduled to undergo mitral valve surgery by cardiopulmonary bypass with estimated mean pulmonary artery pressure =\>55 estimated by using preoperative Doppler echocardiography
Locations
Other Locations
Egypt
Zagazig University
RECRUITING
Zagazig
Contact Information
Primary
Heba M EL-Asser, MD
aseelaswad1@yahoo.com
01062393152
Backup
Amany S abdelazeem, MD
dola.salah2009@gmail.com
01287220016
Time Frame
Start Date: 2023-05-20
Estimated Completion Date: 2025-05-10
Participants
Target number of participants: 38
Treatments
Active_comparator: Group IH(inhaled milrinone)
After induction of anesthesia and stable hemodynamics inhaled milrinone( 1 mg/ml) is initiated and intravenous placebo ( normal saline )infusion are administered
Active_comparator: Group Iv(Intravenous milrinone)
After induction of anesthesia and stable hemodynamics inhaled placebo( normal saline) is initiated and intravenous ( 1 mg/ml) (0.5 μg/kg/min)infusion are administered
Related Therapeutic Areas
Sponsors
Leads: Zagazig University