Copd Exacerbation and Pulmonary Hypertension Trial
Who is this study for? Patients with an acute exacerbation of chronic obstructive lung disease and pulmonary hypertension
What treatments are being studied? Sildenafil
Status: Completed
Location: See all (5) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
This trial will investigate whether patiens admitted with an acute exacerbation of chronic obstructive lung disease and pulmonary hypertension will benefit from a targeted pharmacological treatment.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Healthy Volunteers: f
View:
• COPD verified by specialist and spirometry
• Admitted with the diagnosis acute exacerbation of COPD
• TR-gradient ≥40 mmHg verified by specialist and echocardiography
• Informed consent
Locations
Other Locations
Denmark
Bispebjerg University Hospital
Copenhagen
Herlev-Gentofte Hospital
Copenhagen
Hvidovre Hospital
Copenhagen
Nordsjællands Hospital
Hillerød
Odense Universitetshospital
Odense
Time Frame
Start Date: 2020-02-01
Completion Date: 2024-03-15
Participants
Target number of participants: 250
Treatments
No_intervention: Control
Patients in the control group will receive standard care.
Active_comparator: Sildenafil
Patients in the Sildenafil group will receive standard care and targeted Sildenafil-treatment.
Related Therapeutic Areas
Sponsors
Leads: Chronic Obstructive Pulmonary Disease Trial Network, Denmark